whoa whoa whoa. Lets hit the brakes for a second here. Obviously G you have a serious pain problem and i assure you that Heroin is NOT the answer. In fact though, id say the Oxycontin addiction will probably be harder to break than the Heroin, but the H will kill yah from the inside faster. PLEASE, buddy seek a second opinion, and alternative treatments, which come at the suggestions of the docs you see. Im sure the doc isnt upping your dose because she has a moral issue with getting people severely hooked on pain meds. I applaud her for this, and im sure almost none of her decision is based her not believing how much pain you are in. But of coarse, im not in the room with you and the doc. just understand that these things are SERIOUS drugs, and the downfall to being addicted and abusing things like Heroin, are farrr worse than the actual condition the person has. I know it seems like a horrible thing to say, why not get relief at any cost? because the cost in the end is your life, and the understanding of medical treatments and how they can assist your body over a sometimes long period of time, like physical rehabilitation. In any case i know sever pain, and everyday sever pain is one of the worst things to deal with in life, and drags your entire outlook and quality of life down the drain. It sounds to me like you are scrambling, and are desperate to find relief in any way possible. the only true responsible way to do this is to see multiple doctors and take the recoomendations they give you with as much ferver as possible and attempt to allow yourself the paths to healing, at least through mental means. hopefully medications like marijuana which is harmless when compared to oxy and heroin will be able to assist more in the long run, in some way. but you have to do what your body feels is best, and abusing it with street drugs is def not the answer, you are asking for ten times the problems that you began with. Trust me i understand the need for relief. And do not write with a light heart. but it scares me to think people will turn to street grade heroin for medical relief. as much as docs are useless, they are good sometimes. you just have to find one that understands a plan and can make it work with you. Even the pharms are horrible to have to take, but in the long run, much better than a street version. In terms of cleanliness, safety, and abuse. Man i could go on and on to multiple facts and resonings, but i repeated the necessary. And the acidity in GF juice, or just the juice itself has effects only on a limited line of pills, and as far as i know and have seen on the topic, it doesnt iclude painkillers. Although caffeine will allow a train car for travel with most medicines. Its gives the meds a vehicle to travel the body more efficiently. There are a few ways to accomplish it without caffeine also. Here is just one small ie. of some info behind GF juice, theres all sorts of talk all over, but this sums it all up pretty well// How Grapefruit Juice Makes Some Pills More Powerful - New York Times ."...The handful of drugs now known to be involved include some common and potent ones, among them Plendil (felodipine) for high blood pressure and heart disease, Seldane (terfenadine) for allergies, Sandimmune (cyclosporine) to prevent rejection of transplanted organs, and Invirase (saquinavir) for treating AIDS." Alot was running through the head as i wrote this so if yah have concerns, like, you say youve tried everything, msg me and ill see what resources i can come up with you.