| | my Mom has lupus Conditions and Ailments  |
07-31-2009, 09:17 AM
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#1 | | OG Smokers
Join Date: Jul 2009 Location: Wilmington,,,moving to San Diego then... OAKSTERDAM UNIVERSITY! Gender: 
Posts: 13
Stoner Buck$$: 227.45 | my Mom has lupus
she's been going to the doctors and they keep perscribing her different medications every two weeks or so... (depends on the pill). Since 1989 to today; no luck. Her condition is getting worse, and her pain killers are making her into a different person.
NOW THE REASON FOR THIS POST...
I think a WAY better alternative would be going the medical marijuana route. "What form of lupus do you have? I'll try to stay away from technical terms, but give you some explanation as to why it helps. Basically, lupus is a disease where the body is allergic to itself. Besides destruction to the tissue that is creating the autoimmune response, inflammation, diabetes, arthritis, and oxidative damage can occur to the body as a result of constant immune system activity.
Marijuana has interesting effects on the immune system. Numerous studies identify little effect on the immune system of healthy people, yet can have profound medicinal effects in certain disease pathologies. This is because the cannabinoid receptor exists at a relatively constant amount (very small amount if any) on immune cells of healthy individuals, yet increase in number dramatically during sickness. In doing so, the chemicals secreted by immune cells (called cytokines), that cause inflammation, oxidative damage, and allergic response, can all be decreased in both their production and secretion.
On to fibromyalgia. New studies are now identifying clinical attributes to legitimize the existence of fibromyalgia. Indeed, many doctors believed it to be a myth, as clinical diagnoses focused on checking pain sensitivity in different nerve focal points of the body.
Indeed, EMG (electromyelographs) show a similar electrical stimulatory profile to sensory neuropathy, a disease commonly afflicting diabetics, chemo patients, and those with HIV. Fibromyalgia is definitely a neurological disease. Again, cannabinoids are a great therapy for these situations.
One of the most common ways that heightened pain sensitivty occurs, at least in nerve cells, stems from the phenomenon called excitotoxicity. Nerve cells use neurotransmitters to relay signals between nerve cells. One neurotransmitter, called glutamate, is commonly increased in production and secreted in a much higher concentration than required for normal physiology. When this happens, it increases calcium levels in the nerve cell, by binding to the NMDA glutamate receptor. The NMDA receptor allows calcium channels to open, which allows the calcium to enter the cell from extracellular sources. This excessive calcium then causes numerous signaling cascades that ultimately result in destruction of the cells energy factories (called mitochondria), production of inflammatory and pain signaling molecules (called bradykinins, takykinins, prostaglandins, interleukins), as well as increased production of the gas nitric oxide that also causes neuroinflammation which is especially relevant to fibromyalgia.
The cannabinoid chemicals in marijuana work together to create great therapeutic benefit for fibromyalgia. First, it decreases excessive calcium levels when it binds to the cannnabinoid CB1 receptor. THC can weakly block the NMDA receptor, which means it allows normal physiological functioning of the receptor, without excessive action. Besides activating the cannabinoid rceptor, cannabinoids can directly work as antioxidants, scavenging the free radicals produced from nerve injury and/or constant immune attack against the body. Many of the above mentioned chemical mediators of pain are produced by an enzyme called COX-2. Aspirin is a COX-2 blocker, which is why it blocks pain and minor inflammation. Chemicals in marijuana are also COX-2 blockers.
And finally, cannabinoids can block the transmission of pain at nearly every level of the spinothalamic tract, ascending & descending pain pathways, and the cannabinoid receptors greatest density occurs in the hypothalamis, which can be considerd the integration center of pain transmission." ...I smoke.
so does my dad, tio, all four of my sisters, bro... basically my dad side of the family.
My mom and her husband think of cannabis as an "addictive drug".
HOW DO I GET THROUGH TO THEM?
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08-01-2009, 01:39 AM
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#2 | | Junior Stoner
Join Date: Apr 2009 Location: Canada Gender: 
Posts: 21
Stoner Buck$$: 284.87 | Re: my Mom has lupus
Her pain pills alone can be considered an addictive drug. If shes willing to give all the other drugs a shot, why not try marijuana...its safer and tastier then any other med she will run into. Just show her the TRUE facts about weed and maybe she will come join the greenside. Good luck, and hope she finds somethin that works for her
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08-01-2009, 01:44 AM
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#3 | | Solid.
Join Date: Jan 2008 Location: Grilled Cheese Gender: 
Posts: 6,399
Stoner Buck$$: 5,869.83 | Re: my Mom has lupus
Perhaps also broach the subject without using the word "smoke/smoking". Introduce the concept of edibles, vaporization, any other alternative means. Perhaps also print some good information, with cited references.
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08-01-2009, 05:05 AM
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#4 | | OG Smokers
Join Date: Jul 2009 Location: Wilmington,,,moving to San Diego then... OAKSTERDAM UNIVERSITY! Gender: 
Posts: 13
Stoner Buck$$: 227.45 | Re: my Mom has lupus Quote:
Originally Posted by Osprey Perhaps also broach the subject without using the word "smoke/smoking". Introduce the concept of edibles, vaporization, any other alternative means. Perhaps also print some good information, with cited references. | VEERRYY good ideas (edibles & references). thank you so much(:
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08-01-2009, 07:18 AM
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#5 | | Dutchess of Dank
Join Date: Oct 2008 Location: Magestic Agrestic Gender: 
Posts: 2,078
Stoner Buck$$: 2,507.52 My Mood : | Re: my Mom has lupus i agree with Os, provide information. people that think poorly about MMJ are misinformed. tell your mom that you only want the best quality of life for her, you've done a ton of research for her, and would just like her to let go of any preconceived notions and read the facts. give her time and have patience, it is her treatment and we cannot push something on someone that doesn't want it. talking to her, educating her, dispelling myths....can all be extremely helpful. good luck teeny, and good looking out for you mom.
__________________ (813): I think dad's getting high again. His last google search was "awesome ping pong shit." |
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09-03-2009, 12:17 AM
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#6 | | weed smoking monster
Join Date: Apr 2009 Location: SoCal
Posts: 3
Stoner Buck$$: 203.00 | Re: my Mom has lupus
Hey I just noticed your post about your mom and Lupus. I have Polymyositis [autoimmune disease as well], Fibromyalgia, and Arthritis and all I do now is smoke and eat edibles. I used to be on a bunch of pain medications and valium for my muscle spasms as well as a few others for sleep and nausea, but my only medication now is weed. I don't know if your mom has become more open minded about trying cannabis, but if not, maybe you can share my story. I hope all is well on your end.
Last edited by JPMFM; 09-03-2009 at 12:30 AM.
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